The Department of Physiology and Biophysics - School of Medicine

Confocal Protein Localization

Renal/Kidney
Health Research

Hsp90 localization in renal epithelia
Neuroimaging

Neurological/Brain
Health Research

Digital reconstruction of axonal pathways
Sarcomere

Cardiovascular
Health Research

Localization of myosin binding protein-C (MyBPC) in the cardiac sarcomere
PhD Program

PhD Program
Health Research

Join Our PhD Program and do Groundbreaking Research
Post-Baccalaureate

Post-Baccalaureate
MS in Medical Physiology

Join our program and get your Masters of Science in Medical Physiology
Mouse Cortical Neurons

Neurological/Brain
Health Research

Vascular Endothelial Growth Factor (VEGF) in nerves after moderate hypoxia
Renal Proximal Tubules

Renal/Kidney
Health Research

Na<sup>+</sup>-K<sup>+</sup> ATPase in the basolateral membranes of mouse proximal tubules
Working Heart Perfusion

Cardiovascular
Health Research

Functional analysis of the perfused rat heart

Educational Programs

Faculty

Matthias Buck
Rossana Occhipinti, PhD
Rajesh Ramachandran, PhD
Agustin Gonzalez-Vicente, PhD
Kui Xu, MD, PhD
Tingwei Mu, PhD
Jeffrey L. Garvin, PhD
Walter F. Boron, MD, PhD
Jeffrey R. Schelling, MD
Erika N Allen, PhD
Julian E. Stelzer, PhD
Jessica C. Taylor, PhD
Corey Smith, PhD
Xinghong Dai, PhD
Nami Tajima, PhD
Shiwei Zhu, PhD
Xin Qi, PhD
Fraser J. Moss, PhD
Michael J. Decker, PhD
Patrick Osei-Owusu, PhD, FAHA
Lisa Damato, PhD
Witold K. Surewicz, PhD
Andrea Romani, MD, PhD
George R. Dubyak, PhD

Programs in Aerospace Physiology

Research Mission

Our research mission benefits from a rare combination of faculty who address important translational problems in physiology and biophysics across a broad spectrum of integration—from the level of the atomic structure of molecules, through living cells and organ systems, and up to the whole organism. The major programmatic foci of our research are cardiovascular, renal, and neuronal function in health and disease. Learn more about our Research Laboratories.

Research

Educational Mission

Our educational mission is to provide rigorous training with renown faculty in the environment of Cleveland's world-class healthcare hub. The Physiology and Biophysics Department offers three training programs: Research for the PhD in Physiology and Biophysics prepares trainees to study the function and diseases of the brain, heart, and kidneys. The Master of Science in Medical Physiology enhances the student’s competitiveness for medical school, dental school, and other professional clinical programs. The Certificate in Aerospace Physiology prepares trainees to optimize the performance of astronauts and pilots of high-performance jets, and to advance in careers with NASA, the military, and the civilian space and aviation communities.

Education

News

(May 17, 2024) Medical Physiology Graduate Reception

(Aug. 23, 2024) Annual Department Picnic August 23rd at North Chagrin Reservation

(Oct. 21, 2024) Annual Department Retreat October 21st-22nd at Kalahari

(May 13, 2024) Congratulations to Dr. Shiwei Zui's published paper on Native architecture of a human GBP1 defense complex for cell-autonomous immunity to infection in the Journal of Science.

(May 13, 2024) Osei-Owusu Lab publishes Phosphodiesterases Mediate the Augmentation of Myogenic Constriction by Inhibitory G Protein Signaling and is Negatively Modulated by the Dual Action of RGS2 and 5

(May 13, 2024) Congratulations to Dr. Osei-Owusu's joint paper on Mitochondrial fission inhibition protects against hypertension induced by angiotensin II

(April 8, 2024) Darshan Attmaram receives an Honorable Mention by the APS Physiological Omics Interest Group at the 2024 Physiology Summit

(April 6, 2024) Dr. Xin Qi and Dr. Andrea Romani nominated for the John S. Diekhoff Award for Excellence in Graduate Teaching and Mentoring.

(Jan. 16, 2024) Alethia Dixon Thesis Defense

(Dec. 4, 2023) Recently funded NIDDK R25 grant - PHOL 429 Biophysical modeling and simulation of cellular transport